It will vary from state to state, as to what type of driver's license is permittable to drive on that state's roads.
You will be able to drive when you arrive, but once you settle you must follow the state laws to get licensed, registered and insured in the state.
You will want to contact that state's Department of Motor Vehicles for their rules. Some states are very strict and say once you reside 10 days, you must get licensed and registered while others say 30-45 days. As a rule, once you know you will be a resident of a state and you plan to use the privilege of driving, you should get license and get your vehicle registered in that state.
In general, insurance companies will allow you to purchase an insurance policy with a 'non-US' driver's license. However, they will probably give you 30 days to provide them proof of your valid US driver's license.